Metamizol : In some countries, this medicine may only be approved for veterinary use.

Metamizol proved to be a very effective analgesic. When administered in equipotent doses, it had its effects comparable to various opioid analgesics, such as tramadol, pentazocine and pethidine. Beside the strong analgesic effect, it produces also significant antipyretic and splasmolytic effects without the adverse, unpleasant anticholinergic impact

metamizol is a useful antipyretic both in the adults and children. Its adverse effects are not pronounced and drug interactions are minimal.

Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol. All study medications had a significant antipyretic effect. However,metamizol at the dose 2500 mg was considered as the most effective, while propacetamol at the dose 1000 mg showed the lowest antipyretic efficacy.

Based on the results of the present study, the choice of the antipyretic drug should depend on the clinical status of patient, contraindications, and potential adverse events and risks of the selected agent.

Comparison of the antipyretic effect between ibuprofen, metamizol, nimesulide and paracetamol in children: All the treatments were able to decrease significantly the fever and there was not an statistically significant difference in the antipyretic effects seen in the four groups of treatment.